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Mini-Construct Chamber™
Articles lauding and substantiating InvivoSciences' research, products and technological advancements have been published in more than a dozen recognized and highly credible scientific journals over the last 10+ years. One of our co-founders, Tetsuro Wakatsuki, has contributed to the research and to the subsequent resulting articles, and has become one of the world's most recognized scientists in the area of cell construct technology. Citations include:

 

  • “Three Dimensional Reconstitution of Embryonic Cardiomyocytes in a Collagen Matrix: A New Heart Muscle Model System” T. Eschenhagen,. U Remmers, H. Schoz, J. Wattchow, J. Weil, W. Zimmermann, H. H. Dohmen, H. Schafer, N. Bishopric, T. Wakatsuki, E. L. Elson, FASEB Journal (1997) 11, 683-94.

     

  • “Collagen Receptor Control of Epithelial Morphogenesis and Cell Cycle Progression” M. M. Zutter, S.A.Santoro, J. E. Wu, T. Wakatsuki, S. K. Dickeson, and E. L. Elson, American Journal of Pathology (1999) 155, 927-40.
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  • “A Cell-based Constitutive Relation for Bio-artificial Tissues” G. I. Zahalak, J. E. Wagenseil, T. Wakatsuki, and E. L. Elson, Biophysical Journal (2000) 79, 2369-81.
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  • “Cell Mechanics Studied by a Reconstituted Model Tissue” T. Wakatsuki, M. S. Kolodney, G. I. Zahalak, and E. L. Elson, Biophysics Journal (2000) 79, 2353-68.
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  • “Effects of Cytochalasin D and Latrunculin B on Mechanical Properties of Cells.” T. Wakatsuki, B. Schwab, N. C. Thompson, E. L. Elson, Journal of Cell Science (2001) 114, 1025-36.
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  • “Mechanics of Cell Spreading; Role of Myosin II” T. Wakatsuki, R. B. Wysolmerski, E. L. Elson, Journal of Cell Science (2003) 116: 1617-1625.
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  • “Reciprocal Interactions between Cells and Extracellular Matrix during Remodeling of Tissue Constructs” T. Wakatsuki, E. L. Elson, Biophysical Chemistry (2003) 100, 593-605.
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  • “One-Dimensional Viscoelastic Behavior of Fibroblast Populated Collagen Matrices”, J. E. Wagenseil, T. Wakatsuki, R. J. Okamoto, G. I. Zahalak, and E. L. Elson, Journal of Biomech. Eng. (2003) 125: 719-25.
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  • “Rho-kinase-mediated Calcium-independent Contraction in Rat Embryo Fibroblasts.” D. A. Emmert, J. A Fee, Z. M. Goeckeler, T. Wakatsuki, E. L. Elson, P. Herring, P. J. Gallagher, and R. B. Wysolmerski, American Journal of Physiology – Cell Physiology (2004) 286: C8-21.

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  • “Phenotypic Screening for Pharmaceuticals using Tissue Constructs”, T. Wakatsuki, J. A. Fee, and E. L. Elson, Current Pharmaceutical Biotechnology (2004) 5: 181-189.

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  • “The Heart's Biochemical Response to Hypertension and Exercise” T. Wakatsuki, J. Schlessinger, and E. L. Elson, Trends in Biochemical Sciences (2004) 29(11): 609-17.

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  • “Reconstitution of Frank-Starling Mechanism in Engineered Cardiac Tissues”, , C. F.. Asnes, J. P. Marquez, E. L. Elson, and  T. Wakatsuki Biophysical Journal (2006);91(5):1800-10.
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  • “Engineered tissue models: Innovative tools for early stage, information-dense, high-throughput screening for drug discovery” T. Wakatsuki, K. W. Lieder, and A. Annac, American Biotechnology Laboratory Nov (2006) 24(11) 10-12.

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  • “Tissue Engineering: A New Frontier in Physiological Genomics”, M. C. Petersen, J. Lazar, H. J. Jacob, and T. Wakatsuki, Phys Genomics (2007) 32 28-32.